Head of the Office: Hisato Kobayashi, PhD
Department of Medical Genome Science
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Message from the Head of the Office
The Department of Medical Genome Science is engaged in education and research on the structure, function, and regulation of the genome, which underpins all biological phenomena. We aim to elucidate the mechanisms by which genomic and epigenomic information regulates development, differentiation, and disease, and to explore their clinical applications. We also provide education to medical students and graduate students on the latest developments in genome research and genomic medicine.
Activities
- Mechanisms of genomic imprinting and epigenetic regulation
- Analysis of the epigenome and transcriptome using next-generation sequencing
- Development of novel genomic technologies
- Single-cell multi-omics analysis
- Translational research applying genome information to medicine
- Bioinformatics and data-driven life science
Education
School of Medicine:
1st year | Lecture: Medical Genome Science (from 2026) |
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Research Fields
Epigenetics, gene regulation, functional genomics, single-cell genomics, genome informatics, genomic imprinting, and translational genome medicine.
Academic Society Activities
- The Japanese Society for Epigenetics
- The Molecular Biology Society of Japan
- The Japanese Society of Human Genetics
- The Society for Reproduction and Development
Faculty
Professor Hisato Kobayashi, PhD
Characteristics of the Department
The Department of Medical Genome Science promotes cutting-edge research on epigenomic regulation, with a focus on genomic imprinting and developmental epigenetics. Our research utilizes model organisms and clinical samples to unravel the complexity of gene regulation at the genome-wide level. We also emphasize the development of analytical pipelines for next-generation sequencing and the implementation of translational research in genomic medicine. The department actively fosters collaboration with domestic and international researchers and contributes to the advancement of precision medicine.
Contact
Department of Medical Genome Science
Dokkyo Medical University
Kitakobayashi 880, Mibu, Shimotsuga, Tochigi, 321-0293 Japan