DOKKYO MEDICAL UNIVERSITY

1. We provide advanced team medical care to meet the needs of each patient with heart / vascular and renal diseases. In particular, we have enhanced an emergency system that is available 24/7 , 365 days a year in order to respond promptly and appropriately to the emergency cases of heart, blood vessel, and kidney diseases that are prone to sudden changes.
2. We offer comprehensive cardiovascular rehabilitation for the secondary prevention and prevention of aggravation of heart, vascular and/or renal diseases.
3. At the Graduate School of Medical Engineering, we are collaborating with many facilities in Japan with clinical research themes such as microcirculation, skeletal muscle, exercise, rehabilitation, ultrasonography, and cardiovascular clinical pharmacology. We provide a place for learning and research not only for doctors but also for rehabilitation staff, nurses and clinical engineers. There is a lab meeting (available online) twice a month on the first and third Tuesday evening (PM 6:00-7:00), and attendance is welcomed, so please contact us if you are interested. (tyasu@dokkyomed.ac.jp)  Let’s enjoy and freely discuss together.

     The capillary network and its import / export blood vessels, arterioles and venules, are collectively called the microcirculatory system, and it is an important place for substance exchange and metabolism in the body. Microcirculatory disorders appear from the early stages of all diseases, including diabetes mellitus and hypertension. We visualize the microcirculation with a biomicroscope (sublingual, fingertip) and an ex vivo model, and use it to elucidate the initial pathophysiology of various diseases and evaluate the therapeutic effect. We have developed a device and method for measuring the degree of leukocyte activation in a microvascular model and obtained a domestic patent. "Patent No. 6664608"

Figure 1. Blood flow through a flow path that imitates a blood vessel a) Platelets and white blood cells are activated after smoking and muddy blood (black arrows are activated and adhered white blood cells). The white arrows are red blood cells that deform like folding an umbrella and travel through the flow path. b) Shows the fluidity of smooth blood in which platelets and white blood cells are not activated. Herat & Vessels 2020

      We lose muscle mass by 1% per year after peaking at the age of 25. If we are forced to stay in the hospital because of some disease, we lose 2% of our muscles in a day. Our research theme is to properly evaluate skeletal muscle and athletic ability and develop an appropriate intervention program for nutrition and exercise (including electrical stimulation). "Verification of the usefulness of remote physiotherapy programs by cluster RCT in a community-based comprehensive care system utilizing ICT based on the cardiac rehabilitation method" has been adopted for the large-scale clinical research grant.

     State-of-the-art technology for heart, blood vessels, and skeletal muscle We are conducting evaluation methods and verifications by ultrasonography.

     We have elucidated the mechanism of early diastolic mitral valve regurgitation by recording relative minute pressure differences between the left chambers during early diastole.

• esearch on microcirculation and leukocyte activation

• Development of safer and more effective cardiovascular rehabilitation using skeletal muscle electrical stimulation

• Development of cardiovascular rehabilitation incorporating high-intensity interval training

• Clinical study on suppression of diabetic nephropathy progression

• Research on the treatment of peripheral arterial diseases

• Research on the treatment of cardiomyopathy

• Research on Geriatric problems

Japanese Association of Cardiac Rehabilitation
Japanese Circulation Society
Japanese College of Cardiology
Japanese Society of Internal Medicine
Japanese Association of Cardiovascular Intervention and Therapeutics
Japanese Society of Microcirculation
Japan Society of Ultrasonic in Medicine
Japanese Association of Rehabilitation Medicine

Professor Takanori Yasu, MD, PhD
Assistant Professor Asuka Ueno, MD
Assistant Professor Takushi Sugiyama, MD.
Assistant Professor Atsuhiko Kawabe, MD.
Assistant Professor Takashi Tomoe, MD
Assistant Professor Moe Nagao, MD
Syoya Ono, MD
Eiko Maeno, MD
Satoshi Mizuguchi, MD
Yuma Tamura, PhD. Chief of Department of Rihabilitation

Department of Cardiovascular Medicine and Nephrology,
Dokkyo Medical University, Nikko Medical Center, Nikko, Japan
Prof. Takanori Yasu
tyasu@dokkyomed.ac.jp
See more details → https://www.dokkyomed-nmc-cv.j...(in Japanese)